Unasyn 375 mg Reviews – Antibiotic of the Highest Quality

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Unasyn is a type of antibiotic that belongs to the group of penicillin anti-bacterial drugs. It is a unique formulation that combines the efficacy of Ampicillin and Sulbactam which are both powerful drugs used for the treatment of many types of life-threatening infections. Combining Ampicillin sodium with sulbactam sodium extends the spectrum of Unasyn to include difficult to control bacteria that are typically resistant to ampicillin and beta-lactam antibiotics. This makes Unasyn a potent medication with broader spectrum compared to other antibiotics. Doctors prescribe Unasyn to patients with pneumonia, upper and lower respiratory tract infections, urinary tract infections, tonsilities and post-operative infections. It is also usually the preferred drug to treat severe burns as well as gonorrhea and other sexually transmitted diseases.

Unasyn is commonly used as injectable and adminitered intra-muscularly or intravenously by a medical professional. When injected into the body, this drug usually begins to take effect within 24 to 48 hours, thus giving patients immediate relief from infection-related symptoms like chills and fever. This drug is also favored by many doctors because it causes little or no side effects to patients and is generally well-tolerated. Some reported cases are typical reactions to antibiotics including headache, nausea, skin rashes, renal problems and in some cases, convulsion.

However, this drug is strongly not recommended to patients with known hypersensitivity to ampicillin or sulbactam.

Unasyn is manufactured by leading global pharmaceutical corporation Pfizer.

Unasyn Reviews

Unasyn has received some very good reviews from patients who were prescribed with it after trying other antibiotics that failed to control their infection.

Unasyn ReviewsMJ, a male patient with pneumonia, said “(It) has helped with the septic arthritis too… very soft treatment and very helpful; hope many can have it, too!” He gave the drug perfect score for effectiveness, ease of use and satisfaction.
Unasyn ReviewsAnother young patient, Macey, who is suffering from multiple infection, was said to be responding well to Unasyn. In a response to a comment posted on a health forum site, Macey’s mother said: “She just finished a round of IV Unasyn every six hours and appears to be doing well…”

Overall, Unasyn and its active ingredients Ampicillin and Sulbactam, has been well-received both by patients and their caregivers. In a doctor’s online forum, Unasyn has been mentioned a couple of times as a good drug that they recommend to treat severe infection.

Pricing and Dosages

Unasyn formulation is an off-white dry powder supplied in glass vials. It comes in various packages, as follows:

  • Vials with 1.5 g of Unasyn (1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt)
  • Vials with 3g of Unasyn (2 g ampicillin as the sodium salt plus 1 g sulbactam as the sodium salt)
  • Bottles with 1.5 g Unasyn (1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt)
  • Bottles with 3 g Unasyn (2 g ampicillin as the sodium salt plus 1 g sulbactam as the sodium salt)

It is also supplied in tablet form containing 100mg, 250mg, 375mg and 500 mg of Unasyn.

Unasyn is distributed internationally by Pfizer and is among the higher-priced antibiotics in the market. Price range of 1.5g vial is Rs. 80 to Rs. 100. Maximum dose given to adults, children and elderly who weigh 30 kilograms or more is 375 to 750 mg two times a day for seven days. For children under 30 kilograms, the maximum dose is 50mg/kg daily divided to two doses.

How to Buy Unasyn Online

Unasyn is distributed by Pfizer internationally and it is carried by its accredited online pharmacies with operations worldwide.

How to Use



Unasyn should be strictly used according to the instruction of your doctor. Under-dosing or overdosing can lead to serious medical complication or death. The injectable Unasyn should be stored in a refrigerator and taken out at least one hour before it is injected. Do not re-freeze the vial. It should be administered by a qualified medical professional. Tablets are taken orally along with a little liquid or a bite of food. Store in a cool, dry place. Do not expose to sunlight.

Side Effects

This drug is known to have tolerable side effects and few patients have reported serious illnesses after taking it. Clinical studies have proven it effective, with side effects affecting only a fraction of the patients who were prescribed with this drug. Among the most commonly reported side effects are:

  • Sore throat
  • Headache
  • Skin rashes
  • Diarrhea
  • Chills
  • Flu-like symptoms


Unasyn is one of the top products of Pfizer and is a popular drug among doctors because it is not only effective, it also gives patients little discomfort and causes no major side effects. It is a highly recommended drug that lives up to the Pfizer standard and quality. We can definitely give this drug the highest rating of 5.

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