Eriacta 100mg/50 Tablets Ranbaxy Reviews: Effective Impotence Treatment with an Economical Price

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Eriacta 100mg/50mg is termed as a “generic Viagra” product due to its active pharmaceutical content identical to the legendary erectile dysfunction medication, Viagra. Generic Viagra products are known to circulate the online market and are also famous for their economical prices and similar ingredients with the brand-name treatment. Other generic Viagra products are Kamagra from Ajanta Pharma, Suhagra from Cipla, Fildena from Fortune Healthcare, and a lot more [1].

The drug Eriacta is produced by the pharmaceutical company Ranbaxy, which is recently acquired by the giant company, Sun Pharma, which is also in India [2]. There are innumerable pharmaceutical enterprises situated in the country, which made India famous for its annual pharmaceutical output volume, which contributes largely to the world’s drug supply [3]. Most generic Viagra products are from India and buyers often prefer generics from the country due to their bargain pricing.

Eriacta comes in 100 mg and 50 mg forms [4] and has the same ingredients with the branded Viagra treatment. The product, though, does not have any other variants than the common film-coated tablet and pill types.

About Ranbaxy Laboratories Ltd

Ranbaxy Laboratories Limited is one of the “largest” companies in India [5]. It is comprised of 10,001+ employees who help in the large-scale manufacture of the company’s pharmaceutical products [5]. According to Ranbaxy’s existing LinkedIn profile, the company is the 8th “largest global generic pharmaceutical company” and has its influence in 23 of the world’s top performing markets [5].

Ranbaxy Laboratories was inaugurated in the year 1961 although it went public only in the year 1973 [5]. Today, the company is known to exert its impact in 49 countries where its company has operations in, although its products reach 125 of the world’s countries [5]

Ranbaxy Laboratories

Ranbaxy Laboratories

Though Ranbaxy’s portfolio sounds magnanimously stellar, the top-performing company had a multitude of controversies in the past years. There were reports of falsification of research/lab testing data for some of the products of the company [2]. Whistle-blowers came out in the open to condemn the company’s practice of report fabrication for its pharmaceutical products.

Subsequent to the discovery of the falsified reports, the US FDA ceased its approvals for the products of Ranbaxy due to its falsification of data for the testing [2]. Huge blows were hurled at Ranbaxy in the following years, such as the recall of their proton-pump inhibitors and atorvastatin due to contaminations and mislabeling of the product ingredients [2]. Apart from those, Ranbaxy was also fined $500M due to misinterpreting clinical data and distributing the products in the US [2].

The company seemed to go downhill until its acquisition by Sun Pharma in 2014 [2]. Ranbaxy leveraged the merger to regain its benign status in the pharmaceutical market. Until this day, the company Ranbaxy continues to manufacture pharmaceutical goods, but as a subsidiary of Sun Pharma, whose portfolio includes massive approvals from the US FDA, UK MHRA, Australia TGA, and WHO-GMP amongst other certifications for its product quality [6].

Scientific Studies on Sildenafil

Since the discovery of Sildenafil Citrate for the management of erectile dysfunction, researches were piloted for its benefits’ institution. One of the multi-racial studies conducted for Sildenafil Citrate was one from Lim et al in 2002, “Clinical efficacy and safety of sildenafil citrate (Viagra) in a multi-racial population in Singapore: A retrospective study of 1520 patients”, which evaluated the efficacy, success and the safety of the use of Sildenafil Citrate by men from various racial backgrounds [7]. 912 out of the initial 1520 patients with erectile dysfunction were able to be followed-up by the researchers [7]. Based on the fallout of the study, 83% of the tested patients were able to have satisfactory improvements in their erectile functions (as determined by the GEQ/global efficacy question) [7]. In terms of racial efficacy of the drug, the Chinese had a greater response to the medication (85.7%) compared with the results of the Indian participants (74.2%) and the Malay men (72.8%) [7]. The patients typically responded to 50 mg (49%), but while a number were able to respond to as low as 25 mg (4.1%), a significant number of the population required a higher dose of Sildenafil to realize the optimum efficacy of the drug [7]. Albeit most of the patients were also previously administered with other ED treatments (medicated urethral suppository for erection/MUSE, vacuum devices, traditional medicines), these previous impotence remedies were unable to influence the positive outcome for Sildenafil Citrate [7]. Adverse effects determined for the patients treated with Sildenafil were flushing, headache, blurred vision, giddiness, warmth, and others were recorded in 127 patients [7]. The highest percentage of adverse interaction appearance was only 13.9% of the participants [7].

It was suspected in the past that the adverse effects caused by Sildenafil Citrate were due to its inhibition of diamine oxidase and linked to histamine and its impaired metabolism in the patients’ bodies. To test the hypothesis, the authors Wantke et al conducted their analysis in 2001 entitled “Are adverse effects of sildenafil also caused by inhibition of diamine oxidase?” [8]. The study included 9 volunteers and administered them with Sildenafil Citrate dilutions and was assessed for their in vivo diamine oxidase inhibition [8]. Based on the results, Sildenafil did not inhibit diamine oxidase and as a consequence, the researchers construed that Sildenafil has no effect even for patients with intolerance for histamine [8].

As for other adverse events for Sildenafil Citrate, one case study, the one by Arora et al in 1999, “Acute myocardial infarction after the use of sildenafil” presented a 70-year-old’s case of Sildenafil use and his apparent development of acute myocardial infarction (AMI) post his Viagra consumption and nitroglycerin [9]. The patient had a history of hypertension and hypercholesterolemia and self-administered Viagra (Sildenafil Citrate) and his Nitroglycerin medication [9]. Nitroglycerin and Sildenafil citrate co-administration ensued to the lowering of his blood pressure and aggravated ischemia and caused AMI [9].

Sildenafil in Action

Sildenafil Citrate, in the form of Viagra and generic Viagra products, belongs to the category of PDE5 (phosphodiesterase type-5) inhibitors requisite to the successful erectile response in the males. Due to factors such as disease, aging, lifestyle, and the synaptic signal dysfunction in the patients, the erectile response to sexual stimuli is impaired.

The cGMP (cyclic guanosine monophosphate) which is supposed to have its levels maintained in the penile tissues for the induction of an erection is degraded prematurely by the PDE5 enzyme, which results to poor or failed erections in patients. As a PDE5 inhibitor, Sildenafil Citrate is able to momentarily suppress the action of this PDE5 in order to maintain the proper levels of cGMP necessary to engender an erection in patients (even those suffering from impotence) [4].

Eriacta Effects for Erectile Dysfunction

Eriacta’s positive effect for erectile dysfunction may be expected by the patients due to its ingredients, primarily its Sildenafil Citrate content. PDE5 inhibitors are known to be effective most of the time, for the management of impotence regardless of race [7].

Now that the efficacy of Eriacta is established due to its potent ingredient, the question is, how long does it last? The life of Sildenafil Citrate in the patients’ bodies usually takes an average of 4 hours, but in some cases, the effects of Eriacta, Kamagra/generic Viagra, or Viagra can last up to 6-8 hours, depending on a patient’s metabolism.

How Long Does it Last? Doses and Extent of Therap

Dose recommendations for Sildenafil Citrate are actually variable from patient to patient, albeit the initially prescribed Sildenafil dosage is 50 mg and then titrated to larger or lower doses. Some patients respond to the preliminary 50 mg dose, while others need 100 mg or just 25 mg of the medication [7].

Patients are advised to take Eriacta and other Sildenafil medications on an as-needed basis alone and are restricted to take doses of more than one tablet a day, irrespective of the dose formulation and the effect of the consumed medication.

Side Effects and Warnings

The side effects of Eriacta depend on how long does it last in the body. This means that the adverse events of the drug should only take 4-8 hours or a maximum of 24 hours in the patients, as the drug is metabolized in a period of at most 24 hours and then excreted thereafter.

Common complaints from clients which are considered adverse effects for the Sildenafil medication are flushing, stomach upset, headaches, blurred vision [7], dyspepsia, and stuffy nose [10]. These adverse effects, although imminent, are not able to affect all the users of Sildenafil and occur only to a fraction of the Sildenafil user population.

Drug-to-Drug Interactions

Concomitant use of Sildenafil products like Eriacta, Kamagra, Viagra, and other generic Viagra products with nitrates may result in a critical lowering of the blood pressure, and also myocardial infarction in patients with existing medical considerations [9]. Besides the known interaction between Sildenafil products and nitrates, the product can also interact with the active ingredients of drugs found in the categories of antiviral medicine, antibacterial, antibiotics, HIV meds, AIDS meds, and Hepatitis medication [11]. These drugs should be avoided when taking Sildenafil and patients should be responsible enough to notify their physicians regarding their current medications to receive proper admonitions regarding the safe and unsafe medications to take with Eriacta.

Customer Reviews

Buyer reviews are extremely indispensable in terms of product evaluations. Good thing there were a number of reviews accessible for Eriacta, though most of them were from online pharmacy sites and not review websites:

Eriacta Customer Experience

Eriacta Customer Experience

JM, one reviewer for Eriacta product by Ranbaxy, gave it 5 stars for its performance. He praised the product’s effectiveness although he mentioned that the product was the first erectile dysfunction medication he tried, so he declared that he “can’t compare it to other products”. JM also cited that he had no side effects such as headaches and he felt Eriacta’s effects in about an hour.

Eriacta Customer Review

Eriacta Customer Review

In another online shop, Kamagrauk-shop.com, one user, Luke Davis, gave his feedback for Eriacta. We can say that he was satisfied due to the 5-star rating he gave the product. He also stated that Eriacta was his doctor’s recommendation and said that Eriacta is a “good medicine”.

Is Eriacta Cheaper Than Kamagra and Viagra?

Available forms for Eriacta are the common pill and tablet type, which are not as diverse as other generic Viagra products like Kamagra, which has other forms than tablets and pills. Since the product is manufactured by the famed company Ranbaxy, there are a lot of listings available for the product:

Eriacta Pricing

Eriacta Pricing

Eriacta costs about $0.72-$0.95 each pill on Alldaychemist.com, but aside from the affordable price, the online drugstore even offers freebie tablets on each purchase, even for the minimum 4 pieces of the pills. This pricing is actually better (lower) than most of the generic Viagra medications, for instance, Kamagra, since the product costs a little over $1 each pill in the same online drugstore.

Eriacta Shipping Cost

Eriacta Shipping Cost

Concerning the shipping, the flat charge for all the shipments (including those for the USA, Australia, and Canada) is $25, although Alldaychemist.com has subsidized shipping rates for orders reaching certain amounts and for orders using eChecks, personal checks, money orders, and wire transfer. For instance, orders under $150 using the following payment methods are only charged $15, while those with items more than $150 are charged $5 less at $10. While this promotional offer is exciting for most, this is only valid for purchases on Alldaychemist.com and not applicable for other online drugstores.

Conclusion and Rating

Eriacta 100 mg is another affordable Viagra alternative for the treatment of erectile dysfunction in patients with the disorder. Regarding the product’s efficacy, good reviews were available from the buyers, which reflected their satisfaction for the product. Although the standing of the manufacturing company, Ranbaxy is on a ledge, its merger with Sun Pharma elevated its status from problematic to promising. As for the rating, Eriacta may be granted with 4 out of 5 for its great pricing and good response from the buyers. The other star is reserved for the US FDA approvals – since the drug has not been approved by the US FDA yet, it can only be given a star short of the perfect 5 score. Eriacta is a highly recommended remedy for erectile dysfunction and a decent, cost-effective Viagra generic substitute.

Reference List

  1. http://www.medindia.net/drug-price/sildanafil.htm
  2. https://en.wikipedia.org/wiki/Ranbaxy_Laboratories
  3. https://en.wikipedia.org/wiki/Pharmaceutical_industry_in_India
  4. https://www.1mg.com/drugs/eriacta-50mg-tablet-339888
  5. https://www.linkedin.com/company/ranbaxy
  6. http://www.sunpharma.com/operations/quality
  7. https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~vTWgzY:23:@[email protected]@/cgi-bin/sis/search2/d?./temp/~W7iJtg:[email protected]
  8. https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~vTWgzY:29:@[email protected]@/cgi-bin/sis/search2/d?./temp/~W7iJtg:[email protected]
  9. https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~vTWgzY:22:@[email protected]@/cgi-bin/sis/search2/d?./temp/~W7iJtg:[email protected]
  10. https://www.viagra.com/learning/is-it-right-for-me
  11. http://www.webmd.com/drugs/2/drug-7417-297/viagra-oral/sildenafil-erectile-dysfunction—oral/details#interactions
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