Eregra 100 Pills Sildenafil Citrate Review: Super Force Generic Viagra Alternative

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Eregra 100 mg belongs to the class of the PDE5 (phosphodiesterase type-5) inhibitor drug-type remedies for erectile dysfunction [1]. The pharmaceutical product contains the potent Sildenafil Citrate and not herbal concoctions found in herbal remedies for impotence.

Men diagnosed with impotence usually have immense difficulty in engaging in sexual activities with their partners, due to the physiological tolls of the dysfunction [2]. Impotence is prevalent in the male population, and the men affected by the dysfunction gets younger (more males under 40 are diagnosed with impotence) due to chronic drug abuse, smoking, alcohol, and other forms of substance abuse [3]. Oftentimes, the severity of the younger males’ impotence is greater than the older men’s since drug/substance abuse greatly affects erectile function.

The product Eregra 100 mg is manufactured by the company Varma Pharmacy Limited, which was established in the year 1950 [4]. There is no soft pill, chewable pill, and soft gel capsule forms for Eregra 100; the drug is only retailed in the archetypal hard pill/tablet form. Since the manufacturer is located in India, most of the sale of the drug is observed in the country, although the drug is also vended by local sellers in the United Kingdom, Europe, and some parts of Asia.

About The Varma Pharmacy Pvt Ltd

Varma Pharmacy Pvt. Ltd. is a business native to India (location’s in Pune, India) [5], and with only a few reports available online. Varma Pharmacy has its own website, but the company’s page is unresponsive and inaccessible, therefore further limiting the data we could use for the enterprise. However, there were a few listings on the web for Varma Pharmacy, which can give modest information for the company.

According to the present information for Varma, it has been installed in the year 1950 [4], which makes Varma almost 70 years in the business. The pharmaceutical company is involved in the manufacture of chemical and pharmaceutical products [5] and herbal/Ayurvedic remedies, and beyond that, no other information is available for the nature of the manufacturing Varma is involved in.

Varma Pharmacy Location

Varma Pharmacy Location

Varma Pharmacy runs on its Rs. 500,000 capital ($), which sustains its business until now. As for the accreditations of Varma, the only known approval for the company is its ISO 9001:2000. The data concerning the approvals from various local and international drug commissions are unfortunately unavailable, as the information on Varma’s details is undisclosed.

Clinical Research on Sildenafil

The drug Sildenafil Citrate in the form of Viagra was released and made accessible in the market in the year 1998. Early studies on the drug were conducted during its release and one of the studies regarding the drug was the paper of Orrico et al in 1998, “Sildenafil dose titration program”, which aimed in the determination of the optimum Sildenafil dosage for patients with erectile dysfunction (ED) [6]. Not only the optimum dose was the goal of the study; the researchers also intended to find out the dosage which lessens the event of treatment-emergent adverse effects and the cost-effective dosage for the drug [6]. The dose titrations for Sildenafil were according to protocol; the patients were started on the lowest Sildenafil dosage, and in order to save cost, the patients were asked to split the tablets to achieve the lowest possible dose for Sildenafil [6]. 110 patients completed the treatment, but 11 were on nitrate therapy and were ineligible, while another 3 refused treatment. Of the 96 who were eligible, 14 did not respond to Sildenafil, while the rest had a good response to the medication [6]. 48/96 were able to respond to the 50 mg Sildenafil dose, 30/96 were able to respond to 100 mg, 1/96 responded to 75mg, and 3/96 had a partial response to Sildenafil Citrate’s 100 mg dose. There were adverse events determined and they included stomach pain, headache, skin flushing, lightheadedness, nasal congestion, and groin pain [6].

In 2005, the study of Yaman et al, “Characteristics of sildenafil erections in healthy young men” determined the influence of Sildenafil Citrate on nocturnal erections of healthy, potent young men aged 23-29 years [7]. The participants were given 100 mg on their 3rd night of evaluation (first 2 days were for the establishment of baseline values). Based on the results of the study by the authors, the healthy young men administered with Sildenafil Citrate were able to achieve erections within 34 minutes after their consumption of the drug Sildenafil, which is actually shorter than the proposed claim of the manufacturer (1 hour) [7]. The researchers were also able to determine that the gap between the 1st and 2nd erections were shorter, while the last erection they had when under Sildenafil use was significantly longer than their usual erections without the drug in their system [7].

Sildenafil Mode of Action

Sildenafil Citrate is an active pharmacological ingredient and not just an herbal remedy for impotence. Being a drug which is backed by actual science, its mechanism of action proves effective and efficient in the management of impotence symptoms in the male population.

Sildenafil Citrate, the active content of Eregra, works through enacting its nature as a PDE5 (type-5 phosphodiesterase) inhibitor on the enzyme PDE5, which metabolizes the nucleotide cGMP (cyclic guanosine monophosphate) essential in the furtherance of the erectile function in males, In patients with impotence, since there is a problem with the morphology of the blood vessels supplying the penile tissues, the PDE5 enzyme destroys the cGMP nucleotide even before there is a satisfactory response in erectile function in the males. Sildenafil Citrate as a PDE5 inhibitor warrants the maintenance of the appropriate cGMP levels necessary to potentiate erection in the patients.

Eregra Benefits for Erectile Dysfunction

Since Eregra 100 mg houses an efficacious active ingredient for the remedy of erectile function difficulties, patients can anticipate a palpable amendment in their erectile function with the use of Eregra. The active ingredient of Eregra, Sildenafil Citrate, has been ascertained as an effective impotence treatment by several studies regarding the pharmaceutical ingredient. Albeit a number of herbal medicines claim the same effects too, these remedies cannot compare to the verified efficacy of Sildenafil Citrate and other PDE5 inhibitors when it comes to erectile failure treatment.

Doses Recommendation and Continuation of Therapy

Edegra 100 mg is taken the same way as the brand-name treatment for erectile dysfunction, a singular dose within 24 hours (irrespective of dosage strength), as needed. Edegra works optimally with an empty stomach and lots of water. At the outset, the patients are conferred with 100 mg or 50 mg of Sildenafil depending on the severity of the impotence case of the patients. Edegra can be taken as long as the doctors deem the product useful for the patients, as the intake of Sildenafil products is currently indefinite. There are patients taking the drug for long-term without adverse events and without causing morphological alterations in the patients’ reproductive systems.

Side Reactions and Warnings

Treatment-emergent adverse events may be expected to some extent with the use of Eregra 100 mg and other Sildenafil Citrate product. There are common adverse reactions noted for the use of Eregra due to its Sildenafil Citrate content which is capable of inducing unwanted side effects in the patients.

Typical side effects caused by PDE5 inhibitors such as Sildenafil are headaches, dizziness, bluish vision, blurred vision, dyspepsia, gastric upset, and other events []. These side effects are usually just minor, tolerable, and fleeting, so patients can expect these adverse events to eventually fade after Sildenafil is excreted from the body’s system.

Aside from the ephemeral side effects, patients are also at risk for rare side effects such as chest pains indicative of impending heart attacks, blindness, deafness, ear pounding, nausea and vomiting, muscular pains, seizures, and other “new” side effects caused by Sildenafil in the patients [].

Drug-to-Drug Interactions

Eregra pills, due to its Sildenafil content, also have confirmed drug interactions with other drug families. Sildenafil and nitrate drugs are infamous for their negative effect on the patients. Both nitrate drugs and Sildenafil citrate thereby work conjunctively in decreasing the blood pressure in patients, which could be detrimental.

Besides nitrates like isosorbide mononitrate and dinitrate, nitroglycerin, and other nitrate medication, the patients under Sildenafil/Edegra therapy are charged to veer away from drugs which are classified as antiviral, antibiotic, antibacterial, Hepatitis C and AIDS/HIV medications. Herbal medicines, herbal supplements, vitamin/mineral supplements, and other PDE5 inhibitor drugs are also contraindicated with the use of Sildenafil products like Eregra 100 mg, as they can also wield their effects on the drug.

Customer Reviews

Concerning product reviews for Eregra, there were none available for the product. There were no client criticisms for Eregra 100, either constructive or not. This loss of reviews from buyers is disastrous for the brand, as most of the prospective buyers tend to look up past product feedbacks for reference. We cannot conclude that the brand is effective or futile in the treatment of erectile dysfunction in patients, but the consumers will just assume that Edegra is not worth their time and effort.

However, when we will base our assumptions of the product effectiveness of Eregra from similar generic Viagra brands, we can say that the product may be effectual in the management of impotence symptoms in the patients suffering from erectile dysfunction. Most of the Indian generics sold locally and on the web are most of the time effective alternatives for the brand-name impotence medications and are more often than not more effectual than the herbal remedies for impotence available in the market.

Pricing, Existing Forms, and Available Dosage

The merchandise Eregra is peddled online and locally in several countries (India, the UK, Europe) and is available in 50 mg and 100 mg variants. Although patients may expect other varieties for this generic Viagra product, there are actually no soft versions (soft gel capsule, soft pills, chewable pills) for Eregra; the only form of the product is the orthodox hard pill/tablet form.

Eregra Pricing

Eregra Pricing

There are only a limited number of online sources where patients can purchase of Eregra 100 mg, and one of the online drugstores having the elusive drug in stock is Magicpills.ru from Russia. Based on the price list, the store charges about $2.53 for each Eregra pill, although when the product is bought in 100+ pieces, the cost relegates to $1.13 each.

Eregra Shipping Cost

Eregra Shipping Cost

The online drugstore Magicpills.ru is capable of shipping the product to locations such as the USA, Australia, and Canada, as well as another drugstore, Viabestbuy.com, although the shipping is charged $39 for express. The shipping price is a bit steep, but when buyers actually want the product shipped to them, the price will seem worth it.

There are diminutive restrictions for drug vending online so buyers should be watchful for scammers and rip-off sites whose goal is to siphon money from unsuspecting clients. Buyers should be wary of these risks and take extra caution when dealing with online entities, especially those dealing with retail and money.

Conclusion and Rating

Eregra 100mg/50mg pills are not your regular herbal-type pills, they are actually prescription drugs with the potent Sildenafil Citrate content effective for the management and the remedy of impotence in patients. Though good reviews are typically available for generic erectile dysfunction pills, we are not absolutely sure about the effectiveness of Eregra 100 mg due to its failure to come up with buyer comments relating to the use of Eregra. Owing to this reason, we are only giving the product 2 points out of 5, as no good feedbacks are present to assure us of the product’s beneficial effects.

Reference List

  1. http://www.nytimes.com/health/guides/symptoms/erection-problems/oral-medications-(pde5-inhibitors).html
  2. http://www.healthline.com/health/erectile-dysfunction
  3. http://www.healthline.com/health/erectile-dysfunction/young-men
  4. http://in.kompass.com/c/the-varma-pharmacy-private-limited/in733708/
  5. https://www.zaubacorp.com/company/THE-VARMA-PHARMACY-PRIVATE-LIMITED/U24232MH1950PTC008011
  6. https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~3GD8pJ:21:@[email protected]@/cgi-bin/sis/search2/d?./temp/~tABhi3:[email protected]
  7. https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~3GD8pJ:13:@[email protected]@/cgi-bin/sis/search2/d?./temp/~tABhi3:[email protected]
  8. http://www.webmd.com/drugs/2/drug-7418-589/sildenafil-oral/sildenafil-20-mg-lungs—oral/details#side-effects
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