Enthusia 100mg/50mg Tablet Lupin Review: Cheaper than Viagra, yet Quality Sildenafil Brand

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Enthusia 100mg/50mg Tablet Lupin is a high-quality generic brand of Viagra, having sildenafil as acting component. It comes in tablets of 50 mg and 100 mg. Being a brand of one of the leading pharmaceutical manufacturing company of India, one can be sure that the only difference between Enthusia and Viagra is the cost.

Erectile dysfunction (ED) or commonly known as impotence in men is a rising problem globally. ED is a chronic problem disturbing the sexual life of more than half of men above 40 years of age [1]. Poor sexual life leads to psychological problems in men and deteriorates their relationship with a partner.

Sildenafil since its launch became the most effective and trusted treatment for ED or impotence. ED is commonly caused due to psychological problems like stress and depression or due to neurovascular pathologies. These neurovascular pathologies are often the secondary result of diseases like diabetes, high blood pressure, high cholesterol or surgery [1].

Sildenafil benefits in ED far outweigh the risks. Most of the men suffering from ED have found it to be highly beneficial at doses 50 mg to 100 mg. Precaution should be taken if a person has suffered a heart attack or have irregular cardiac rhythms. Some medicine may interact with sildenafil, therefore it is always advisable to consult a physician before starting to use it.

About Lupin Ltd

Lupin Ltd is truly global company from India. Established in 1968, it has continually grown to become one of the leading companies in India. For the last decade, it has successfully maintained its position among top 10 pharmaceutical companies in India. Lupin Ltd is one of the leading suppliers of generics in the world, with a presence in markets like US, Japan, and most European countries.

Lupin Main Office

Lupin Main Office

Lupin Exports more than 100 products worldwide. It has more than 18 manufacturing facilities world over. Its manufacturing plants are approved by World Health Organization (WHO), TGA (Australia), US FDA, MHRA (UK), MHLW (Japan), MCC (South Africa) and ANVISA (Brazil), and have subsidiaries in many European countries. It is one of the leading companies by sales volumes in the USA, Japan, South Africa and many other countries [2].

It is one of the leading companies in the anti-infective segment, other segments in which company is a significant player are a cardiology, diabetes, Pediatrics, nervous system diseases, Gastrointestinal drugs.

It is also one of the most research-oriented company from the Indian subcontinent. The company employees more than 1700 scientists in various locations in India, US and Europe. It invests more than 10% of its sales in R&D and has more than 2000 patents in its portfolio till date.

Clinical Studies on Sildenafil

When it comes to scientific studies and evidence of effectiveness and safety, sildenafil is surely one of the well-studied molecules. There is an abundance of studies serving as a proof of its benefits to men suffering from ED or impotence.

In one of the scientific review article by Gamidov SI et al. titled “Sildenafil Citrate in the Treatment of Men with Erectile Dysfunction”, the author noted that sildenafil is the effective treatment of ED, regardless of etiology, seriousness and age group of the patient. As it affects the blood flow to the penis, hence it is highly effective in ED of vascular origin. It provides quick and long-lasting relief from the symptoms of ED. It is well tolerated and does not cause addiction in short or long term [3].

Successful treatment of ED not only improves the quality of life of men but also their sexual partners. In sexual relationship satisfaction of partner is very important, and can serve as a valuable indicator of the success of treatment. Most of the studies try to focus on the sexual satisfaction of the patient and neglecting the satisfaction level of partner. In a study titled “Partner Responses to Sildenafil Treatment of Erectile Dysfunction” Pomerantz TS et al. studied the satisfaction rate of a partner after the use of sildenafil. In 10 sildenafil trials, they gave the questions to a partner regarding frequency of erection, the ability to maintain it and overall satisfaction with sex. While in 4 more trials they used EDITS partner questionnaire to evaluate the partner’s satisfaction level. Partners of men treated with sildenafil reported the much higher level of sexual satisfaction and improvement in partner’s ability to achieve and maintain an erection as compared to placebo group. EDITS index score was 64 in the treatment group as compared to 43 in the placebo group. Hence from the feedback by partners of treated men, it can be concluded that sildenafil is highly effective in improving sexual life of couples [4].

Male potency is considered to be a direct indicator of health. Poor health and disease conditions lead to a decrease in male potency. Wrong dietary habits are one of the main reasons for fall in male potency. It is no secret that alcohol has a highly negative effect on potency, but being addictive in nature many men find it difficult to stop. Men who take alcohol regularly, earlier or later in life face the problem of ED. Sildenafil is helpful in such cases. Grinshpoon A et al. carried out the study titled “Sildenafil Citrate in the Treatment of Sexual Dysfunction and Its Effect on Quality Of Life in Alcohol-Dependent Men: Preliminary Findings.” to find out how helpful is sildenafil in alcohol-dependent men. 54 patients took part in the 12-week long study. Results of therapy were analyzed using International Index of Erectile Function (IIEF), and another questionnaire regarding the quality of life. In the end of the trial, significant improvement was reported, both in sexual function and quality of life. Hence it can be concluded that sildenafil is helpful in ED caused due to excessive alcohol use [5].

Sildenafil Action Explained

The anatomical structure which plays a most important part in penile erection is called corpus cavernous or cavernous body. It is soft sponge-like tissue body, making the major part of the male penis. These sponge-like tissues when filled with blood on sexual arousal lead to erection in men. Longer the blood remains in the cavernous body, stronger and longer will be an erection. The penis becomes placid when blood leaves this cavernous body. Sildenafil increases blood flow to this cavernous body and also helps to hold this blood for longer in it, thus increasing both the hardness and duration of erection. All this happens due to the blocking of an enzyme called phosphodiesterase 5 (PDE 5), which is responsible for softening of penile tissues.

Enthusia Effects for Erectile Dysfunction

Enthusia is a drug that helps to increase blood flow to the penis on sexual arousal, and it also increases the duration of erection by helping to hold blood longer. Increased hardness and duration leads to successful and satisfactory sexual life in men. Though sildenafil has also been shown beneficial in some other disease conditions like pulmonary arterial hypertension, but doses used for that purpose are lower. Enthusia is mainly used to increase male potency.

Recommended Doses and Length of Therapy

For most men, 50 mg once a day 30 min or one hour before the sexual act can produce the desired results. Though some men may need a higher dose of 100 mg, this is especially true for men dependent on alcohol or having other disease conditions like diabetes.

Though most men start with 50 mg, but after few years many of them switch over to 100 mg, as lower dose becomes less effective. There is no defined duration of therapy, and it is no secret that ED is a chronic problem, and often related to age in men. Sildenafil has been tested for long term use and has been shown to be safe.

Adverse Effects and Possible Warnings

Most of the side effects of sildenafil are temporary: they last only as long as you continue taking the drug. Most common side effects reported are a flushing of face and headache, smaller number report loss in appetite and palpitation.

In rare cases, a person may feel changes in vision and hearing, these side effects though rare may become main reason to discontinue the therapy [6].

Though sildenafil is safe for healthy hearts, precaution should be taken if someone had suffered a stroke or heart attack. Precaution should be taken if someone is suffering from any kind of cardiac problem, in such cases, it is advised to consult a physician before initiating a therapy [7].

Drug Interactions

Sildenafil slightly dilates all blood vessels, this may result in little fall in blood pressure in some individuals. It may also potentiate the clinical effect of some antihypertensive drugs, hence precaution should be taken when on antihypertensive therapy.

It is absolutely contraindicated in people taking nitrates, the drugs prescribed for certain cardiac conditions. Sildenafil has been demonstrated to cause significant fall in blood pressure when taken with nitrates, which can be dangerous for life [8].

All drugs are eliminated from our body via metabolism, some drugs may disturb the metabolism of sildenafil and thus increasing the level of drug in the blood. In such cases, one may need to decrease the dose. Drugs which are known to increase the concentration of sildenafil in blood are erythromycin, cimetidine, ketoconazole, Itraconazole [8].

Customer Reviews

In the days of online shopping, we all take buying decisions only after reading customer reviews. In the case of Enthusia, customer reviews are absent; hence, it is natural that we feel doubtful about the quality of the drug.

In such cases, when customer reviews are not available, it is advisable to read customer reviews of other similar drugs to learn more about the component. Hence, it is advised to read more about Viagra, Kamagra or Sildenafil before making a buying decision.

Another way to know more about the quality of drug is to find information about the manufacturer, in the case of Enthusia it is well known and reputed company.

Price, Forms, and Suitable Dosage

Enthusia Price

Enthusia Price

The product is available in the strength of 50 or 100 mg. It is sold in tablet form. The product is quite reasonably priced at half a dollar for one tablet of 100 mg.

Enthusia Shipping Cost for USA

Enthusia Shipping Cost for USA

Enthusia Shipping Cost for UK

Enthusia Shipping Cost for UK

Of course, you will need to pay extra for shipping. Shipping costs will vary and from country to country, and will also depend upon the shipping method chosen. Usually, untraceable shipment is much cheaper in comparison to the trackable parcel.

For most of the men, it is better to start with 50 mg of Enthusia, and if the effect is not as expected than better increase to 100 mg. One should not take more than one tablet a day.

Conclusion and Rating

Sildenafil is a clinically proven solution of impotence in men. As more and more men want to have healthy and happy sexual life, demand for sildenafil and its analogs has risen. The effectiveness of this drug is supported by tons of clinical trials and millions of satisfied men.

Though the customer reviews for Enthusia are absent in online world, considering that its manufacturer is a big and reputable company, I would give Enthusia 4 stars out of 5, as most of the manufacturing facilities of this company are under strict quality control and it simply cannot afford to produce the low-quality product.

Reference List

  1. Causes of ED. Available from: http://www.nhs.uk/conditions/Erectile-dysfunction/Pages/Introduction.aspx
  2. Global Manufacturing. Available from: http://www.lupin.com/global-manufacturing.php
  3. http://europepmc.org/abstract/med/25799737
  4. http://search.proquest.com/openview/c15606e531b55ddfdee1c1f97127d107/1?pq-origsite=gscholar&cbl=46833
  5. https://www.ncbi.nlm.nih.gov/pubmed/17537832
  6. http://link.springer.com/article/10.1023/A:1015056416501
  7. http://www.health.harvard.edu/mens-health/are-erectile-dysfunction-pills-safe-for-men-with-heart-disease
  8. http://www.aafp.org/afp/2000/0315/p1745.html
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